Osteopathy Articles and Abstracts

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Osteopathy Journal Articles



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Readers respond to 'osteopathic physician' identity
Rentz, L. E. (1994), J Am Osteopath Assoc 94(1): 30.

Real risks of HIV transmission to physicians and their staffs. American Osteopathic Association Task Force on AIDS
Calabrese, L. (1992), J Am Osteopath Assoc 92(1): 109-11.
Abstract: This series will provide brief clinical updates and perspectives on the human immunodeficiency virus (HIV). It was developed from the AOA Task Force on AIDS Writers' Workshop, held August 16 to 18, 1991, in New York, and sponsored by an education grant from Burroughs Wellcome. A related editorial appears on page 63. Readers may request tear sheets from the AOA editorial offices.

Records to assist osteopathic physicians
Kelso, A. F. (1975), J Am Osteopath Assoc 74(8): 751-4.

Recruiting interns and residents to an osteopathic medical training program
Slick, G. L. (1992), J Am Osteopath Assoc 92(5): 654-6.
Abstract: As more graduates of colleges of osteopathic medicine enroll in allopathic training programs and specialty programs, medical directors of osteopathic medical institutions are faced with the challenge of maintaining a well-trained housestaff. More important, perhaps, this exodus threatens the very core of osteopathic medicine, namely, its ability to produce well-trained primary care physicians. A recruitment plan used at the Chicago College of Osteopathic Medicine and its affiliates is presented here. The plan emphasizes the importance of trainee involvement in their own education as well as the use of residents in recruiting interns and specialty residents.

Re-examining the number of osteopathic residency programs
Baker, H. H. (1998), J Am Osteopath Assoc 98(2): 77.

Regression of hypertrophic osteopathy following pneumonectomy in a dog
Madewell, B. R., T. G. Nyland, et al. (1978), J Am Vet Med Assoc 172(7): 818-21.
Abstract: Hypertrophic osteopathy was diagnosed clinically and radiographically in a 6-year-old English Bulldog. Pneumonectomy to remove a primary pulmonary fibrosarcoma resulted in rapid regression of clinical signs and soft tissue enlargement of the limbs and gradual but incomplete regression of periosteal new bone formation over a 15-month postoperative course.

Regression of hypertrophic osteopathy following removal of intrathoracic neoplasia derived from vagus nerve in a dog
Hara, Y., M. Tagawa, et al. (1995), J Vet Med Sci 57(1): 133-5.
Abstract: Surgical removal of an intrathoracic tumor derived from a vagus nerve was undergone in a dog with hypertrophic osteopathy. The tumor was pathologically diagnosed as malignant schwanoma. Soft tissue swelling, lameness, and itchiness in four limbs disappeared within 7 days after surgery. The proliferated periosteal osteophytes of the four limbs was progressively reduced with time by follow-up radiography on the 58th day after surgery. On the 710th day after surgery, these osteophytes were greatly decreased as osteopathy, malignant schwanoma.

Regression of hypertrophic osteopathy in a cat after surgical excision of an adrenocortical carcinoma
Becker, T. J., R. L. Perry, et al. (1999), J Am Anim Hosp Assoc 35(6): 499-505.
Abstract: A 12-year-old, spayed, female domestic shorthair cat was diagnosed with severe and extensive hypertrophic osteopathy of the appendicular skeleton. Diagnostic ultrasound detected a mass lesion in the right adrenal gland. A right adrenalectomy was performed, and histopathological examination confirmed an adrenocortical carcinoma. No radiographic evidence of pulmonary metastasis was found on initial presentation or recheck thoracic radiographs taken 15 weeks later. Almost complete regression of periosteal new bone formation occurred 15 weeks following the successful surgical removal of the adrenal tumor.

Regression of hypertrophic osteopathy in a dog following unilateral intrathoracic vagotomy
Watson, A. D. and W. L. Porges (1973), Vet Rec 93(9): 240-3.

Regression of hypertrophic osteopathy in a filly following successful management of an intrathoracic abscess
Chaffin, M. K., W. W. Ruoff, et al. (1990), Equine Vet J 22(1): 62-5.

Relationship between academic achievement and student performance on the Comprehensive Osteopathic Medical Licensing Examination-USA level 2
Evans, P., L. B. Goodson, et al. (2003), J Am Osteopath Assoc 103(7): 331-6.
Abstract: The Comprehensive Osteopathic Medical Licensing Examination-USA (COMLEX-USA) is a three-part examination used for licensing osteopathic physicians. The relationship between performance on this examination and prior student academic performance has been unclear. This study explores the relationship between COMLEX-USA level 2 scores and student academic performance at Oklahoma State University College of Osteopathic Medicine (OSU-COM). All first-time examination candidates from OSU-COM had a formal, weeklong board review in March 2000, and all passed the examination. Predictions about COMLEX-USA scores generated by the academic dean's office at OSU-COM underestimated student examination performance; results suggest a significant correlation between level 2 performance with (1) level 1 performance (751); (2) grade point average (GPA) in basic science (659); (3) total GPA (672); and (4) Medical College Admission Test (MCAT) scores (406). The correlation of level 2 scores to clinical GPA (269) was lower but still significant. Results of this study suggest that performance on COMLEX-USA level 2 is strongly correlated with prior student academic performance in this population.

Relationship of osteopathic medical licensure examinations with undergraduate admission measures and predictive value of identifying future performance in osteopathic principles and practice/osteopathic manipulative medicine courses and rotations
Meoli, F. G., W. S. Wallace, et al. (2002), J Am Osteopath Assoc 102(11): 615-20.
Abstract: Two hundred sixty-five students from four classes at one school of osteopathic medicine were studied to determine the correlation between several frequently used premedical admission criteria to predict performance on the early and current versions of the osteopathic medical licensure examinations. Further analysis evaluated the predictive value of the examination of the National Board of Osteopathic Medical Examiners (NBOME) and its successor, the Comprehensive Osteopathic Medical Licensing Examination-USA (COMLEX-USA) in determining subsequent performance in the ascending levels of the examination sequence, as well as to predict performance in the courses and rotations of osteopathic principles and practice (OPP) and osteopathic manipulative medicine (OMM). This study also investigated the relationship between the early and later parts of the osteopathic medical licensure examinations. Analysis showed that of all premedical parameters, only the Medical College Aptitude Test score was positively correlated with performance on COMLEX-USA. In addition, a positive correlation was demonstrated between the performance in either Level 1 of COMLEX-USA or in the earlier form of the NBOME examination Part I and subsequent performance on the current Level 2 of COMLEX-USA or the old NBOME Part II. Finally, analysis indicated that COMLEX-USA predicted performance in OPP knowledge and skills.

Relationship of preadmission variables and first- and second-year course performance to performance on the National Board of Osteopathic Medical Examiners' COMLEX-USA Level 1 examination
Baker, H. H., M. K. Cope, et al. (2000), J Am Osteopath Assoc 100(3): 153-61.
Abstract: The purpose of this study was to examine the relationship of performance on the Comprehensive Osteopathic Medical Licensing Examination (COMLEX-USA) Level 1 licensing examination to (1) academic performance during the first 2 years of the curriculum, and (2) preadmission grade point averages (GPAs) and Medical College Admission Test (MCAT) scores for one osteopathic medical school with the unique mission of providing osteopathic family physicians for West Virginia and rural Appalachia. Simple correlations were calculated for the 63 students at West Virginia School of Osteopathic Medicine who completed all requirements of the first 2 years of the curriculum in May 1998 and were first eligible for board exams in June 1998. These included 26 (41.3%) female students and 5 (7.9%) minority students. Students who had failed a year and/or a course but subsequently successfully completed the first 2 years of the curriculum in May 1998 were included in this study. Every student who qualified to take the June 1998 administration of COMLEX-USA Level 1 did so at that time. For the 55 academic or preadmissions variables of interest, correlation coefficients with COMLEX-USA Level 1 scores and significance levels were calculated using SPSS Base 9.0. The correlation of COMLEX-USA Level 1 performance with GPA for Phase I was 0.64; with GPA for Phase II, 0.67; and total GPA for the first 2 years, 0.70. Grades in most individual courses also correlated significantly with COMLEX-USA Level 1 performance. Given the special focus of this curriculum on the needs of the Appalachian region and use of clinical performance measures or participation measures in calculating academic GPAs, these correlations show a remarkable degree of agreement between these two sets of performance measures. Further research is needed to see if similar relationships exist for osteopathic medical schools with other missions and with other curriculum structures. Preadmissions GPAs and MCATs did not significantly relate to performance on COMLEX-USA Level 1.

Renal biopsy: a 9-year study at an osteopathic referral center
Flood, M. T. and G. L. Slick (1983), J Am Osteopath Assoc 83(4): 285-93.

Report of the 1987 National Survey of Osteopathic Hospitals
Kennedy, B. (1987), Osteopath Hosp Leadersh 31(5): 20-1.

Research at US colleges of osteopathic medicine: a decade of growth
Guillory, V. J. and G. Sharp (2003), J Am Osteopath Assoc 103(4): 176-81.
Abstract: Although research is a critical component of academic medicine, it has not been a significant component of osteopathic medicine. For years, leaders in the osteopathic medical profession have called for increased research in osteopathic medical schools. The need for cost-effective clinical practice leading to improved clinical outcomes creates a necessity for conducting well-designed clinical outcomes research related to osteopathic practice. The authors assess the growth in research at osteopathic academic medical centers from 1989-1999. The amounts of extramural funding at each school, sources of funding, types of research funded, departments funded, and investigators' degree types are also assessed. During the 10 years analyzed, total research funding increased 37%. Twenty-five percent of the grants and 55% of the funding to colleges of osteopathic medicine were from the National Institutes of Health. Most (63%) grants were awarded to PhD faculty. Most research was conducted in the basic biomedical sciences. Clinical research related to osteopathic practices appears to be a relatively minor component of research at osteopathic medical centers.

Research development at the University of Health Sciences College of Osteopathic Medicine
Guillory, V. J. (2001), J Am Osteopath Assoc 101(5): 265-7.

Research in action: a summary of the 2001 American Osteopathic Association Research Conference
Prozialeck, W. C. (2002), J Am Osteopath Assoc 102(3): 117-9.

Research lacking in osteopathic medical profession
Wood, D. L. (1997), J Am Osteopath Assoc 97(1): 23.

Research programs of the AOA and their role in osteopathic education
Retz, K. C. (1990), J Am Osteopath Assoc 90(11): 1027-32.

Research programs of the AOA and their role in osteopathic medical education
McGill, S. L. and K. C. Retz (1998), J Am Osteopath Assoc 98(11): 627-31.

Research programs of the AOA and their role in osteopathic medical education
Retz, K. C. (1991), J Am Osteopath Assoc 91(11): 1147-52.

Research programs of the AOA and their role in osteopathic medical education
Retz, K. C. (1992), J Am Osteopath Assoc 92(11): 1418, 1425-9.

Research programs of the AOA and their role in osteopathic medical education
Retz, K. C. (1993), J Am Osteopath Assoc 93(11): 1167-8, 1173-6.

Research programs of the AOA and their role in osteopathic medical education
Retz, K. C. (1994), J Am Osteopath Assoc 94(11): 951-2, 957-60.

Research programs of the AOA and their role in osteopathic medical education
Retz, K. C. and S. L. McGill (1996), J Am Osteopath Assoc 96(11): 679-83.

Research programs of the AOA and their role in osteopathic medical education
Retz, K. C. and S. L. McGill (1997), J Am Osteopath Assoc 97(11): 678-82.

Research secures the future of osteopathic medicine: Part 1. Research--foundation for faculty development, institutional recognition
Papa, F. J. (1993), J Am Osteopath Assoc 93(5): 606-10.
Abstract: The first of a two-part feature examining the role of research in securing the future of osteopathic medicine, this article describes the historical development of research, specifically how it has come to symbolize valued intellectual and institutional markers in society. Administrators of colleges of osteopathic medicine are called on to increasingly support research-related activities to fully develop the intellectual potential of their faculty. Only through faculty development can osteopathic medical training institutions achieve their fullest potential and thereby secure a stable future for the profession.

Research secures the future of osteopathic medicine: Part 2: Readdressing the function and structure of colleges of osteopathic medicine
Papa, F. (1993), J Am Osteopath Assoc 93(6): 701-4, 707-8.
Abstract: Many problems exist within the contemporary medical education process in general and the osteopathic medical profession in particular. Part 2 of this series suggests that the single greatest impediment to solving these problems is an institutional infrastructure that is not congruent with the institution's functions, as defined in its mission statement. (This mission statement generally entails two primary goals: education and research). Two major divisions within the core's infrastructure are suggested: medical education and medical research. By restructuring their infrastructure, colleges of osteopathic medicine can more effectively address and support their primary functions of education and research.

Research under osteopathic auspices
Chapman, L. F. (1962), J Osteopath (Kirksvill) 69: 18-22.

Researched and demonstrated: inquiry and infrastructure at osteopathic institutions
Gevitz, N. (2001), J Am Osteopath Assoc 101(3): 174-9.

Resolution of paraneoplastic leukocytosis and hypertrophic osteopathy after resection of a renal transitional cell carcinoma producing granulocyte-macrophage colony-stimulating factor in a young Bull Terrier
Peeters, D., C. Clercx, et al. (2001), J Vet Intern Med 15(4): 407-11.

Resorptive osteopathy in inflammatory arthritis (absorptive arthritis, opera glass hand)
Silver, M. and O. Steinbrocker (1954), Bull Hosp Joint Dis 15(2): 211-22.

Resources in bioethics at osteopathic medical schools
Peppin, J., K. Leeper, et al. (2002), Acad Med 77(5): 427-31.
Abstract: PURPOSE: Medical students must have some exposure to bioethics, whether it be at the undergraduate or the postgraduate level. The authors sought to determine the range and ranking of topics taught in bioethics courses at U.S. osteopathic medical schools. METHOD: A qualitative study using a repeated-measures design was used to determine curricular offerings at all 19 U.S. osteopathic medical schools. Nominal groups were held to identify an initial topics list. A modified reactive Delphi technique was constructed and three survey iterations were administered. RESULTS: Bioethics is taught in all osteopathic medical schools, although the numbers of hours dedicated to the subject in the course of a four-year curriculum vary greatly (range 0-40). To further differentiate a curriculum in bioethics, the respondents were asked to rank bioethics topics as essential, foundational, or peripheral to the undergraduate medical curriculum. A total of 16 topics, including confidentiality, informed consent, truth-telling, death and dying, palliative care, and refusal of care, were identified as "essential" for a bioethics curriculum. CONCLUSIONS: Bioethics is taught at osteopathic medical schools, but further studies are needed to recommend guidelines to standardize the curriculum.

Results of a survey of inaugural class graduates of a college of osteopathic medicine
Nichols, K. J. (2003), J Am Osteopath Assoc 103(1): 9-15.
Abstract: The purpose of this study was to determine where the graduates of an inaugural class of a college of osteopathic medicine came from, what influenced their school selection, how their osteopathic medical school experience affected them, and how they chose what and where they would study after graduation as well as where they would practice. These data have significant implications for the osteopathic profession and its future recruitment efforts into the profession and into its postgraduate programs.

Revamped osteopathic hospital group flourishing
Burda, D. (1992), Mod Healthc 22(21): 29.
Abstract: Once on the brink of extinction, a restructured, relocated American Osteopathic Hospital Assn. is "well on the way to achieving its new mission," one observer says. The rebirth follows a near merger with the American Hospital Assn. in August 1990. Under new leadership, the group is growing, making money and expanding its advocacy of osteopathic medicine.

Revisiting the role of osteopathic manipulation in primary care
Abend, D. S. (1999), J Am Osteopath Assoc 99(2): 88-9.

Revisiting the role of osteopathic manipulation in primary care
Hopp, R. J. (1999), J Am Osteopath Assoc 99(2): 88.

Rhabdomyolysis and severe haemolytic anaemia, hepatic dysfunction and intestinal osteopathy due to hypophosphataemia in a patient after Billroth II gastrectomy
Altuntas, Y., M. Innice, et al. (2002), Eur J Gastroenterol Hepatol 14(5): 555-7.
Abstract: Hypophosphataemic syndromes lead to appreciable morbidity and mortality. A deficiency or lack of phosphate leads to tissue hypoxia and disruption of cellular function, which may cause severe clinical complications. We present various manifestations of hypophosphataemia; in all cases, diagnosis was delayed due to lack of follow-up. We present the case of a patient with rhabdomyolysis, severe haemolytic anaemia, hepatic dysfunction and intestinal osteopathy due to hypophosphataemia complicated by gastric Billroth II anastomosis surgery. We also review the literature concerning hypophosphataemic conditions. In conclusion, the determination of serum calcium and phosphate levels should be included in the routine follow-up of Billroth II anastomosed patients.

Rheumatoid lung nodulosis and osteopathy associated with leflunomide therapy
Rozin, A., M. Yigla, et al. (2005), Clin Rheumatol: 1-5.
Abstract: BACKGROUND: Leflunomide (LEF) is indicated in adults for the treatment of active rheumatoid arthritis (RA). LEF inhibits dehydroorotate dehydrogenase, a key enzyme of the pyrimidine synthesis in activated lymphocytes. Among rare adverse effects, fatal interstitial lung disease has been recently reported during treatment of RA with LEF in Japan. Clinical trials outside Japan do not suggest that LEF causes an excess of pulmonary adverse effects. Development and increase of peripheral rheumatoid nodules in typical sites of RA patients following LEF therapy has been recently reported. OBJECTIVES: Two cases with new and accelerated development of rheumatoid lung nodulosis during LEF therapy were described in this study. METHODS: LEF treatment was administered to two male patients (77 and 66 years old) with long-standing active seropositive nodular RA with failure of multiple second line drugs and without lung involvement. Clinical and laboratory assessment using the American College of Rheumatology response criteria, chest computed tomography (CT), quantification of serum rheumatoid factor (RF), and monocyte count of peripheral blood along with routine laboratory follow up were performed on both patients before and during therapy. In case 1, a bone scan was performed due to sustained limbs pain. Open lung biopsy was performed in case 1 and core lung biopsy in case 2. RESULTS: Both patients achieved full clinical remission during 2 months of LEF therapy. In case 1, the first complaints were limbs pain after 10 months of treatment associated with intensive bone uptake on a bone scan consistent with hypertrophic pulmonary osteopathy. Productive cough developed after 3 months of the therapy in case 2. Initially, these complaints were not attributed to therapy. New lung disease was present on CT with cherry-like progressive cavitary nodules, predominantly involving the basal segments of the right lung. The first lung lesions were found by CT 13 months (case 1) and 7 months (case 2) after the beginning of therapy and were erroneously related to bronchiectasia in case 2. In both cases, the lung biopsy showed necrosis surrounded by epithelioid mononuclear inflammation with giant cells, consistent with rheumatoid lung node. The time that elapsed between the beginning of the first symptoms to LEF discontinuation was very long: 13 months in case 1 and 24 months in case 2. Discontinuation of LEF therapy was followed by an arrest in growth of lung nodules, resolution of limb pain, and gradual improvement of bone scan. A significant decrease of monocyte count and RF level in peripheral blood was observed during LEF therapy in both cases. CONCLUSION: For the first time, we described rheumatoid lung nodulosis as complication of successful LEF therapy for RA. Hypertrophic pulmonary osteopathy with severe limbs pain and dry cough were the first manifestations of the lung nodulosis. Monocytopenia during LEF therapy is proposed to be involved in pathogenesis of this rare complication of LEF therapy.


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