| For medical practitioners and osteopaths - Osteopathy Journal Articles Catalog. |
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| Hypertrophic osteopathy associated with an intrathoracic neoplasm in a rabbit DeSanto, J. (1997), J Am Vet Med Assoc 210(9): 1322-3. Abstract: Hypertrophic osteopathy associated with an intrathoracic neoplasm was diagnosed in a 7.5-year-old spayed female White New Zealand rabbit. The rabbit was examined because it had a swollen foot and was anorectic. An intrapulmonary mass as well as periosteal proliferation in the tarsometatarsal region were observed on radiography. Histologic examination of necropsy specimens was used to confirm the diagnosis of hypertrophic osteopathy secondary to metastatic adenocarcinoma of the lungs. To the author's knowledge, hypertrophic osteopathy has not been reported in lagomorphs, but should be considered as a differential diagnosis in lame rabbits. |
| Hypertrophic osteopathy associated with Mycobacterium fortuitum pneumonia in a dog Wylie, K. B., D. D. Lewis, et al. (1993), J Am Vet Med Assoc 202(12): 1986-8. Abstract: Mycobacterium fortuitum was isolated from the lung of a dog that had new periosteal bone formation consistent with hypertrophic osteopathy. Fever, weight loss, and bilateral hind limb lameness were the initial clinical signs. The tarsi were swollen and a pain response was elicited on palpation of the hind limb. Radiography revealed periosteal new bone formation on the metatarsi, femurs, and ischii. Thoracic radiography revealed pulmonary mass lesions in the right middle and left caudal lung lobes. After right middle and left caudal lung lobectomy, M fortuitum was isolated from the excised tissues. Amoxicillin trihydrate/clavulanic acid and amikacin were administered, on the basis of susceptibility test results. |
| Hypertrophic osteopathy associated with ovarian carcinoma in a mare van der Kolk, J. H., S. N. Geelen, et al. (1998), Vet Rec 143(6): 172-3. |
| Hypertrophic osteopathy in a dog with a chronic lung abscess Hesselink, J. W. and J. G. van den Tweel (1990), J Am Vet Med Assoc 196(5): 760-2. Abstract: A 2-year-old dog was examined because of gradual lameness of all 4 limbs and weight loss. Hypertrophic osteopathy was diagnosed. Radiography revealed a mass in the caudal lobe of the right lung. At necropsy, the mass was determined to be a chronic abscess. Corynebacterium pyogenes was cultured from the lesion. Although hypertrophic osteopathy in dogs is commonly associated with a thoracic lesion, most often neoplastic, the chronic lung abscess in this dog might have been formed as a result of a paralaryngeal abscess that was treated 3 months before the onset of the lameness. |
| Hypertrophic osteopathy in a pony with a pituitary adenoma Sweeney, C. R., K. E. Stebbins, et al. (1989), J Am Vet Med Assoc 195(1): 103-5. Abstract: Hypertrophic osteopathy was diagnosed in a pony that had no antemortem or postmortem evidence of an intrathoracic lesion. With a history of hirsutism in an aged pony, a pituitary adenoma was suspected, and evaluation of plasma cortisol and insulin values and their response to thyrotropin-releasing hormone supported the diagnosis. |
| Hypertrophic osteopathy in a Shetland pony attributable to pulmonary squamous cell carcinoma metastases Leach, M. W. and R. R. Pool (1992), Equine Vet J 24(3): 247-9. |
| Hypertrophic osteopathy in an alpaca Curtis, C., A. J. Dart, et al. (1997), Aust Vet J 75(1): 61-2. |
| Hypertrophic osteopathy in rats following chronic administration of SDZ MNS 949, an isoquinoline Langle, U. W., S. Bruggemann, et al. (1994), Exp Toxicol Pathol 45(8): 473-9. Abstract: SDZ MNS 949, 6,7-dimethoxy-3-methyl-1-(3',5'-bis (methoxyethoxy) phenyl)-isoquinoline, a bronchodilating anti-inflammatory drug that inhibits phosphodiesterase, had been proposed for the treatment of bronchial asthma. Groups of 14 male and 14 female Wistar rats were administered doses of 12, 50, and 130 mg/kg/day in feed for 26 weeks. Periodic radiographic examinations were performed in addition to clinical observations, clinical chemistry measurements and urinalysis. At study termination full necropsy and histopathological examinations were performed on all animals. The principal clinical signs observed were unilateral edematous, red and painful swelling of the distal hindlimbs in 8 of 28 high dose animals, and abdominal swelling in 19 of 28 high dose animals. At radiographic examination periosteal new bone formation was predominantly along the tibia. Lesions at necropsy included dilated small and large intestines. Microscopically, enteritis was observed, and the periosteal new bone formation was confirmed. Hematological findings consisted of thrombocytosis and lymphocytosis, especially in high dose animals. The clinical, radiographical and histological findings in treated rats were consistent with the diagnosis of "hypertrophic osteopathy" or "Marie's Disease". |
| Hypertrophic osteopathy in three horses and a pony Lavoie, J. P., G. P. Carlson, et al. (1992), J Am Vet Med Assoc 201(12): 1900-4. Abstract: Hypertrophic osteopathy was diagnosed in 3 horses and in a pony, ranging in age from 8 to 21 years. There were 2 females, 1 sexually intact male, and 1 gelding. In 3 animals, hypertrophic osteopathy was associated with pulmonary abscesses, bronchogenic squamous cell carcinoma, and ovarian granulosa-cell tumor, respectively, and resulted in death or euthanasia. Duration of the condition ranged from 1 to 4 months. In 1 horse, hypertrophic osteopathy was believed to be secondary to pregnancy, and resolved following uncomplicated delivery of a live foal. |
| Hypertrophic osteopathy--an unusual but treatable condition Shneerson, J. M. (1990), Equine Vet J 22(1): 1-2. |
| Hypertrophic pulmonary osteopathy associated with granular cell tumour in a mare Heinola, T., M. Heikkila, et al. (2001), Vet Rec 149(10): 307-8. |
| Hypertrophic pulmonary osteopathy in a steer Merritt, A. M., D. C. Dodd, et al. (1971), J Am Vet Med Assoc 159(4): 443-8. |
| Hypocalcemia and osteopathy in mice with kidney-specific megalin gene defect Leheste, J. R., F. Melsen, et al. (2003), Faseb J 17(2): 247-9. Abstract: Megalin is an endocytic receptor highly expressed in the proximal tubules of the kidney. Recently, we demonstrated that this receptor is essential for the renal uptake and conversion of 25-OH vitamin D3 to 1,25-(OH)2 vitamin D3, a central step in vitamin D and bone metabolism. Unfortunately, the perinatal lethality of the conventional megalin knockout mouse model precluded the detailed analysis of the significance of megalin for calcium homeostasis and bone turnover in vivo. Here, we have generated a new mouse model with conditional inactivation of the megalin gene in the kidney by using Cre recombinase. Animals with a renal-specific receptor gene defect were viable and fertile. However, lack of receptor expression in the kidney results in plasma vitamin D deficiency, in hypocalcemia and in severe bone disease, characterized by a decrease in bone mineral content, an increase in osteoid surfaces, and a lack of mineralizing activity. These features are consistent with osteomalacia (softening of the bones) as a consequence of hypovitaminosis D and demonstrate the crucial importance of the megalin pathway for systemic calcium homeostasis and bone metabolism. |
| Hypocalcemia, hypovitaminosis d osteopathy, osteopenia, and secondary hyperparathyroidism 32 years after jejunoileal bypass Haria, D. M., J. D. Sibonga, et al. (2005), Endocr Pract 11(5): 335-40. Abstract: Objective: To detail, for the first time, the results of bone histomorphometry, micro-computed tomography, and the calcium-vitamin D-parathyroid hormone (PTH) axis in a unique patient 32 years after undergoing a jejunoileal bypass (JIB) procedure for obesity. Methods: A case report is presented, serial results of serum chemistry studies before and after treatment are outlined, and histomorphometric data on a bone biopsy specimen are summarized. Results: In a 65-year-old woman with chronic lymphedema who had undergone JIB >3 decades earlier, baseline serum studies showed the following: total calcium, 6.2 mg/dL (normal, 8.5 to 10.5); ionized calcium, 0.87 mmol/L (normal, 1.15 to 1.35); creatinine, 1.3 mg/dL (normal, 0.6 to 1.0); albumin, 2.0 g/dL (normal, 3.0 to 5.0); magnesium, 1.0 mg/dL (normal, 1.5 to 2.1); phosphorus, 3.1 mg/dL (normal, 2.5 to 4.5); potassium, 3.1 mEq/L (normal, 3.5 to 5.0); alkaline phosphatase, 204 U/L (normal, 50 to 136); PTH, 311 pg/mL (normal, 10 to 60); 25-hydroxyvitamin D, <7 ng/mL (normal, 10 to 60); and 1,25-dihydroxyvitamin D, 37 pg/mL (normal, 25.1 to 66.1). Histomorphometry of an undecalcified iliac crest bone biopsy specimen demonstrated increased osteoid surface of 59.4% (Z-score = 5.6), increased mineralization lag time of 90.1 days (Z-score = 2.96), decreased adjusted apposition rate of 0.05 mm(3)/mm(2)/yr (Z-score = -2.45), but increased volume-based bone formation rate of 0.715 mm(3)/mm(3)/yr (Z-score = 2.0). Tetracycline labeling was diffuse and smudged, and the osteoblast-osteoid interface was decreased, indicating a mineralization defect. Increased cortical porosity, but no evidence of significant marrow fibrosis, was noted, whereas cancellous bone volume was decreased to 15.2% (Z-score = -0.92). Micro-computed tomography of bone biopsy specimens confirmed both increased cortical porosity and decreased cancellous bone volume. Vitamin D and calcium therapy resulted in near-normal or low-normal levels of 25-hydroxyvitamin D and calcium and improvement in PTH and alkaline phosphatase levels during a 9-month period. Conclusion: Significant hypovitaminosis D osteopathy, osteopenia, and hypocalcemia attributable to vitamin D deficiency may remain a problem in patients with unreversed JIB operations after more than 3 decades. Clinicians should be aware of this important clinical problem. |
| Idiopathic multifocal osteopathy in four Scottish terriers (1991-1996) Hay, C. W., R. T. Dueland, et al. (1999), J Am Anim Hosp Assoc 35(1): 62-7. Abstract: This case series describes four Scottish terriers with an osteopathic condition, characterized by multifocal absence of bone in the skull, cervical spine, and proximal radii, ulnae, and femora. All dogs were affected clinically; two dogs were euthanized due to progression of the disease, one died acutely, and one was euthanized for an oral melanoma. Histopathology in one case was characterized by osteoclastic osteolysis and replacement of bone with fibrous tissue. This disease has some characteristics of human osteolysis syndromes. Three of the dogs were related through pedigree analysis, and the pedigree of the other dog was not available. The name, idiopathic multifocal osteopathy, is used to describe a new disease in dogs, found particularly in Scottish terriers. |
| Implementation of an osteopathic manipulative medicine clinic at an allopathic teaching hospital: a research-based experience Przekop, P. R., Jr., H. Tulgan, et al. (2003), J Am Osteopath Assoc 103(11): 543-9. Abstract: Mastery of osteopathic palpatory skills and the skilled delivery of osteopathic manipulative treatment is a life-long venture that demands from practitioners increasingly sophisticated manual skills. Specific receptors and neural networks within the brain allow for the gradual development of refined manual skills that parallel responsive alterations and refinements that develop with repeated experience. During clinical training, most graduates of colleges of osteopathic medicine are not given opportunities to hone their palpatory skills. This is unfortunate because there is an increasing public demand for the nonpharmacologic treatment modalities osteopathic physicians could supply. At Berkshire Medical Center in Pittsfield, Mass, a major teaching affiliate of the University of Massachusetts Medical School in Worcester, the authors assembled a team of osteopathic and allopathic physicians to found an osteopathic manipulative medicine clinic. In this article, the authors share their experience in the creation of this research-based osteopathic medical clinic. |
| Improving functional ability in the elderly via the Spencer technique, an osteopathic manipulative treatment: a randomized, controlled trial Knebl, J. A., J. H. Shores, et al. (2002), J Am Osteopath Assoc 102(7): 387-96. Abstract: Twenty-nine elderly patients with preexisting shoulder problems voluntarily enrolled as subjects in this study, which was undertaken to determine the efficacy of osteopathic manipulative treatment (OMT) in an elderly population to increase functional independence, increase range of motion (ROM) of the shoulder, and decrease pain associated with common shoulder problems. Each subject had chronic pain, decreased ROM, and/or decreased functional ability in the shoulder before entering the study. Subjects were randomly assigned to either a treatment (OMT) group or a control group for 14 weeks. Over the course of treatment, both groups had significantly increased ROM (P <.01) and decreased perceived pain (P <.01). All subjects continued on their preexisting course of therapy for any concurrent medical problems. After treatment, those subjects who had received OMT demonstrated continued improvement in their ROM, while ROM in the placebo group decreased. |
| Improving the oral health knowledge of osteopathic medical students Skelton, J., T. A. Smith, et al. (2002), J Dent Educ 66(11): 1289-96. Abstract: Due to a complex set of circumstances including culture, poverty, low educational achievement, and limited access to dental care, the oral health of rural Appalachians is poorer than that of people in other parts of Kentucky. Limited health care dollars go to primary medical care which may be the only contact these individuals have with the health care system. Consequently, primary care physicians can help improve oral health. The University of Kentucky College of Dentistry (UKCD) and the Pikeville College School of Osteopathic Medicine (PCSOM) developed an oral health education block for third-year PCSOM students. Eleven UKCD faculty and one PCSOM faculty participated in the two-day, sixteen-hour oral health curriculum. Knowledge retention data from the post-tests was collected four months after the educational program. Students significantly improved their performance in six of the topic areas, with performance staying the same in one area and dropping significantly in one area. Focus groups were conducted with sixteen (two groups of eight) randomly selected students one year after the educational program. Students reported using the knowledge and oral exam techniques included in the course and felt that it was a valuable addition to their curriculum. |
| In pursuit of generalism: basic factors influencing the specialty decisions of osteopathic medical school seniors in 1995 Singer, A. M. (1996), J Am Osteopath Assoc 96(11): 699-703. Abstract: An analysis of survey responses of seniors graduating from osteopathic medical school in 1995 shows that the selection of the medical specialty they planned to pursue in their postgraduate training was considerably influenced by 10 common factors. These factors ranged from the students' orientation to people or techniques, to prestige and income associated with the specialty. The People orientation factor exerted a strong influence on students planning to pursue primary care specialties (defined as Family Practice, General Internal Medicine, and General Pediatrics) Similarly, for students planning to pursue a nonprimary care specialty, the Prestige/income, the Intellectual Content factor, and the Research Factor, with its absence of stress and opportunity for research in other nonprimary care fields, swayed their decision. These findings have implications for the medical school admissions process. If that process can be used to identify students who relate well to people and are more oriented to dealing with preventive medicine and the broad spectrum of health problems presented by individual patients, then it could become an even greater force in the movement toward generalism in medicine. |
| Incidence, etiology, diagnosis, and treatment of recurrent urolithiasis: results of a 5-year study at an osteopathic referral center Cianciolo, K. D., R. W. Wadle, et al. (1983), J Am Osteopath Assoc 82(8): 577-83. |
| Inclusion of evidence-based medicine in colleges of osteopathic medicine and suggestions for implementing evidence-based medicine into osteopathic medical school curricula Cundari, A. D. and N. Ker (2003), J Am Osteopath Assoc 103(11): 557-64. Abstract: The authors investigated the extent to which colleges of osteopathic medicine include evidence-based medicine education in their curricula. Information was obtained through a questionnaire survey, including a Likert scale. The survey was sent to 19 colleges of osteopathic medicine for completion. Twelve responses were received within the time limits of this cross-sectional study, yielding a 63% response rate. Four colleges of osteopathic medicine report that they currently teach evidence-based medicine within their education programs. Variations among the programs included the type of faculty delivering the evidence-based medicine course, the years in which instruction occurs, the number of hours of instruction, and assessment methods used. Seven additional schools have plans to implement evidence-based medicine into their educational programs. Suggestions for the design of an evidence-based medicine course and an evidence-based medicine-based curriculum are discussed in relation to the survey results. |
| Inclusion of osteopathic orthopedists in workforce studies Mikutis, J. L. (2001), Orthopedics 24(6): 529. |
| Income and expenditures of osteopathic medical colleges Kowert, C. (1998), J Am Osteopath Assoc 98(11): 595. |
| Income and expenditures of osteopathic medical colleges Rayman, C. (1996), J Am Osteopath Assoc 96(11): 660-1. |
| Income and expenditures of osteopathic medical colleges Rayman, C. (1997), J Am Osteopath Assoc 97(11): 644-5. |
| Income and expenditures of osteopathic medical colleges Reich, M. (1992), J Am Osteopath Assoc 92(11): 1389-90. |
| Income and expenditures of osteopathic medical colleges Reich, M. M. (1993), J Am Osteopath Assoc 93(11): 1153. |
| Income and expenditures of osteopathic medical colleges Reich, M. M. (1994), J Am Osteopath Assoc 94(11): 937. |
| Increased awareness of osteopathic medicine is essential to the profession's survival Clark, R. C. (2000), J Am Osteopath Assoc 100(1): 6-8. |
| Increasing osteopathic manipulative treatment skills and confidence through mastery learning Mann, D. D., D. C. Eland, et al. (2000), J Am Osteopath Assoc 100(5): 301-4, 309. Abstract: Several recent studies document the declining use of osteopathic manipulative treatment (OMT) in clinical practice. In this article, the authors contend that developing new teaching materials based on the mastery learning approach can augment time-tested methods of teaching OMT and help to stop or reverse this decline. The Spencer technique for shoulder manipulation is used to demonstrate the development and evaluation of OMT mastery learning materials. These materials could be developed as part of a progressive teaching sequence requiring increasing diagnostic acumen, palpatory skill, and therapeutic subtlety. Such a program could be used throughout osteopathic medical training and for continuing medical education to increase skills and confidence in the use of OMT. |
| Industrial medicine and the osteopathic general practitioner Grace, J. M. (1961), J Am Osteopath Assoc 61: 195-200. |
| Infantile cortical hyperostosis (Caffey-Silverman syndrome). Animal model: craniomandibular osteopathy in the canine Thornburg, L. P. (1979), Am J Pathol 95(2): 575-8. |
| Influenza and its osteopathic management. 1937 Ward, E. A. (2000), J Am Osteopath Assoc 100(5): 325-8. |
| Influenza epidemic or pandemic? Time to roll up sleeves, vaccinate patients, and hone osteopathic manipulative skills D'Alonzo, G. E., Jr. (2004), J Am Osteopath Assoc 104(9): 370-1. |
| Institutional impact of a part-time faculty development fellowship program for osteopathic community-based physicians Pinheiro, S. O., D. K. Liechty, et al. (2002), J Am Osteopath Assoc 102(11): 637-42. Abstract: Evaluation of faculty development programs for medical educators has often focused on the satisfaction of individual learners. Long-term outcomes of skills and knowledge acquired during faculty development programs have been more difficult to evaluate. The impact on the institutions where the "developed" faculty teaches has been even less studied. This article discusses the results of a survey that focused on the institutional impact of a year-long part-time faculty development fellowship program for community-based physician faculty. The Statewide Campus System of Michigan State University College of Osteopathic Medicine (SCS MSU-COM) faculty development program conducted a survey of its graduates to ascertain the impact on the educational processes in their home institutions and the impact of the program on the graduates as medical educators. Responding graduates reported increased use of educational concepts and greater participation in the educational activities of their home institutions. The study demonstrates that a faculty development program addressing the needs of community-based physician faculty changes the perceptions of participants as medical educators and appears to have a positive impact on the educational process in their home institutions. |
| Integrate osteopathic principles and practices in postgraduate medical education--now Kasovac, M. and J. M. Jones, 3rd (1993), J Am Osteopath Assoc 93(1): 118, 123-5. Abstract: We issue a call for an "osteopathic medical renaissance" in teaching osteopathic principles and osteopathic manipulative techniques. This article describes a seminar series in the postdoctoral training program at the College of Osteopathic Medicine of the Pacific. We ask osteopathic physicians to enhance their manual dexterity skills to better serve as role models for physicians-in-training. We challenge osteopathic physicians to stimulate a renewed emphasis in teaching distinctive osteopathic medical care. |
| Integrating cranial osteopathy with gnathologic orthopedics Kennedy, J. M. (1998), J Am Acad Gnathol Orthop 15(2): 4-7 contd. |
| Integrating cranial osteopathy with gnathologic orthopedics Kennedy, J. M. (1998), J Am Acad Gnathol Orthop 15(3): 4-9. |
| Integrating osteopathic training into family practice residencies Johnson, K. H., J. A. Raczek, et al. (1998), Fam Med 30(5): 345-9. Abstract: BACKGROUND AND OBJECTIVES: Since the mid-1980s, the number of osteopathic graduates has increased, and the number of osteopathic hospitals has decreased. This has led to an increasing number of osteopathic students seeking training in Accreditation Council for Graduate Medical Education (ACGME) family practice residency programs. In response to these developments and to a declining pool of allopathic applicants in the early 1990s, at least 35 ACGME programs have completed the American Osteopathic Association (AOA) accreditation process as approved internship sites. This article describes 1) the rationale for becoming accredited, 2) the AOA accreditation process, 3) a model osteopathic curriculum, 4) potential difficulties, 5) issues to consider in approaching a decision to become AOA accredited, and 6) future trends in osteopathic graduate medical education. |
| Interdisciplinary approach to teaching medication adherence to pharmacy and osteopathic medical students Singla, D. L., G. E. MacKinnon, 3rd, et al. (2004), J Am Osteopath Assoc 104(3): 127-32. Abstract: The purpose of this project was to demonstrate to pharmacy and osteopathic medical students the value of interdisciplinary education through participation in an interdisciplinary medication adherence project. Each pharmacy student, assuming the role of a pharmacist, was paired with a medical student acting as a physician with a needlestick exposure requiring HIV prophylaxis therapy. Medical students were randomized to participate in one of three levels of pharmacist counseling. After completion of therapy, all students met to discuss adherence barriers, complete an attitudinal survey, and obtain a tablet count. Most pharmacy and medical students agreed or strongly agreed that participation in this project will help them work better within the health care team (82% and 87%, respectively) and that they should have more participation in interdisciplinary projects (83% and 76%, respectively). At the end of the project, these students reported positive attitudes concerning working on interdisciplinary health care education initiatives. |